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Don’t Let the Immune Response Blindside You: The Importance of Early Immunogenicity and Immunotoxicity Assessment

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Presented by: Noel Smith, head of immunology, Lonza Pharma & Biotech Biopharmaceutical developers are keenly aware of high attrition during preclinical drug development stages. Immunogenicity and immunotoxicity concerns account for many program failures. Thus, developers strive to identify safety concerns as early as possible. By detecting problems early, companies can reengineer their molecules, investigate process-related solutions, or select alternative lead candidates. Smith reviewed methods that Lonza has developed to enhance early immunogenicity and immunotoxicity studies. Smith noted that several factors…

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